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(2) nuclear translocation of NF-B

[DOI] [PubMed] [Google Scholar] 30.Hosseini S, Rezaei S, Moghaddam MRN, Elyasi S, Karimi G

Notably, the in vivo pharmacokinetic evaluations in a Sprague Dawley rat model revealed a 16.8-fold increase in plasma half-life and a 16.1-fold improvement in oral bioavailability compared to native GSH

This conditional model contains a Cre recombinase fused to a mutant estrogen ligand binding domain (CreERT2) that is activated by the estrogen antagonist tamoxifen