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Additionally, docosanoid-dependent signaling plays a role in corneal nerve regeneration, tear formation, and wound healing

To test the involvement of NRF2, we bred the Gclc f/f mouse strain with the Nrf2 f/f mouse strain 57,58 and induced a liver-specific double deletion with the AAV-TBG-Cre virus (hereafter referred to as L-DKO) (Fig

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Erastin and icFSP1 are specific inhibitors of both ferroptosis defense systems and have been used in the treatment of various diseases (34,35)