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[PubMed: 14168179] 590

Additionally, pathway-specific interventions, such as AR inhibitors, AGE cross-linking inhibitors, AGE/RAGE signaling pathway inhibitors, selective PKC- inhibitors, and HBP inhibitors, have demonstrated potential to suppress oxidative stress and ROS generation from the earliest stages of hyperglycemia-induced vascular damage

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These sessions can extend the duration of the initial effects and contribute to long-term skin health