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For example, gene therapy has been used to reduce P-gp expression at the BBB, and RNA interference (RNAi) technology has been employed to silence the P-gp gene [86]

Probiotics have been linked to prevent and/ or treat acute diarrheal infections, necrotizing enterocolitis, antibiotic-related diarrhea, pediatric colic, allergies, lactose intolerance, ulcerative colitis, Helicobacter pylori infection, Crohns disease, metabolic illnesses, neurological diseases, and respiratory tract infections (Liu et al., 2018