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The study found that: Between the 4th and 12th week, 50% of participants on Varenicline abstained from smoking, as opposed to 16.9% of participants on the placebo

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A rat basophilic leukemia cell line, RBL-2H3 representing mucosal type mast cells [19], which has been extensively applied in studies of mast cell biochemistry and signalling, was used as an in vitro model of mast cells for this study