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As pointed out above, activated AMPK stimulates energy-producing processes but inhibits energy-consuming anabolic processes, especially protein synthesis, by antagonizing mTOR kinase (Inoki et al., 2012)

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As the primary centers of energy production within cells, mitochondria are severely affected by ischemic damage [65, 66]

This review highlights how the probiotic field is advancing beyond traditional applications to encompass NGPs, live biotherapeutics, genetically engineered microbes, and rational microbial consortia