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Studies have reported that in mice with impaired BCAA degradation, BCAA accumulates in CD8 + T cells, resulting in high-activity CD8 + T cells and enhanced anti-tumor immunity [22] (Fig

Hum Genet 122:355365 Alcolea V, Plano D, Karelia DN, Palop JA, Amin S, Sanmartin C, Sharma AK (2016) Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines