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Koeth RA, Levison BS, Culley MK, Buffa JA, Wang Z, Gregory JC, Org E, Wu Y, Smith JD LL, et al

Most sorbitol is made from corn syrup, but it is also found in nature, for example in apples, pears, peaches, and prunes

Furthermore, oxidative stress activates multiple stress-responsive signaling pathways and alters gene expression profiles, which further disrupts cellular metabolism and physiological processes

Mitochondrial dysfunction as an arrhythmogenic substrate: a translational proof-of-concept study in patients with metabolic syndrome in whom post-operative atrial fibrillation develops