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& Parthasarathy, M

However, when ROS levels rise beyond the capacity of antioxidants, they can damage cellular macromolecules, disrupt normal cell functions, trigger mitochondria to produce pro-apoptotic proteins, and ultimately lead to the apoptosis of central nervous system neurons (Schieber and Chandel, 2014)

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Weighted Gene Co-expression Network Analysis (WGCNA) identified a coexpression gene module which associated with resistance and enriched with the genes involved in oxidative stress response, secondary metabolism, and cell wall reinforcement