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After carefully reading the 212 articles, we excluded 125 articles because of the following reasons: no necessary data ( n = 73), paper was retraced ( n = 1), markers were analyzed in animal model ( n = 2), without an HC (n = 24), samples were not from serum or plasma ( n = 21), samples were from adult patients with ASD ( n = 4)

Research has shown that NAD+ levels tend to decline with age, and some studies suggest that boosting NAD+ levels through supplementation might have potential benefits for certain aspects of ageing

Nowadays there is no doubt that pathogenesis of OLP is germane to development of oxidative stress, which can become the reason of immune insufficiency and can cause chronic pathologic process [3, 106-107

Psoriasis is a chronic autoimmune skin condition characterized by the rapid buildup of skin cells, resulting in thick, red patches of inflamed skin covered with silvery scales